Abstract Objectives Intra-device thrombosis remains one of the most common complications during extracorporeal membrane oxygenation (ECMO). Despite anticoagulation, approximately 35% of patients develop thrombi in the membrane oxygenator, pump heads, or tubing. The aim of this study was to describe the molecular and cellular features of ECMO...
Abstract Background Assessment of bleeding phenotype is critically important in the diagnosis of von Willebrand Disease (VWD). Despite advances in Bleeding Assessment Tools (BATs), standardised tools to evaluate bleeding following diagnosis (interim bleeding) are lacking. Objectives We assessed the clinical utility of an interim bleeding protocol in a multicentre,...
Abstract Background Severe COVID-19 disease is associated with thrombotic complications and extensive fibrin deposition. Here, we investigate whether the haemostatic complications in COVID-19 disease arise due to dysregulation of the fibrinolytic system. Methods This prospective study analysed fibrinolytic profiles of 113 patients hospitalized with COVID-19 disease with 24 patients...
Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundThe evidence linking vitamin D (VitD) levels and spontaneous intracerebral hemorrhage (ICH) remains inconclusive. We tested the hypothesis that lower genetically determined VitD levels are associated with higher risk of ICH.Methods and...
Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundThe GWTG (Get With The Guidelines)‐Stroke registry supports clinical research and quality improvement projects that often rely on past medical history elements, the reliability of which remains largely unknown. Here, we evaluated...
Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundChagas disease is a neglected tropical disease that is still considered a global health emergency. In the Amazon region, most of the reports are of acute cases that are associated with oral...
Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundAs patients derive variable benefit from generator changes (GCs) of implantable cardioverter‐defibrillators (ICDs) with an original primary prevention (PP) indication, better predictors of outcomes are needed.Methods and ResultsIn the National Cardiovascular Data...
Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundBecause body mass index (BMI) is generally used clinically to define obesity and to estimate body adiposity, BMI likely is positively correlated with epicardial adipose tissue (EAT) level. Based on echocardiography, previous...
Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundHypertension and diabetes frequently coexist; however, it has not yet been clarified if the bidirectional longitudinal relationships between arterial stiffness and hypertension are independent of those between arterial stiffness and diabetes.Methods and...
Journal of the American Heart Association, Volume 11, Issue 13, July 5, 2022. BackgroundAcute aortic syndromes may be prone to misdiagnosis by nonreferral aortic centers with less diagnostic experience. We evaluated regional variability in these misdiagnosis trends among patients transferred to different regional quaternary care...
